CS3.2 Efficacy of common antifungal drugs

Pharmacodynamics of Antifungal Drugs: A Strategy to Optimize Efficacy

Pharmacodynamic studies examine the relationship between drug pharmacokinetics and outcome. These investigations have been shown to be helpful for the design of dosing intervals, choice of optimal dose levels, and the development of susceptibility breakpoints. Pharmacodynamic studies with available antifungal agents have been useful in developing optimal dosing regimens to improve efficacy and ...

Antifungal drugs.

Working in the medium of batik, Paul Nzalamba creates images that are drawn from his native country, Uganda, and that reflect the strength, struggle, and beauty of all people, especially children and adolescents. We chose to use his “At Play” (1988) to show a modern, indigenous artist’s work that illustrates the color and joy of such artists. Mr. Nzalamba’s works are on display at his studio in...

Antifungal Drugs

GENERIC NAME PAGE Amphotericin B 596 Butoconazole 601 Capsofungin 601 Ciclopirox 602 Clotrimazole 600 Econazole 601 Fluconazole 598 Flucytosine 601 Griseofulvin 602 Itraconazole 599 Ketoconazole 599 GENERIC NAME PAGE Miconazole 600 Naftifine hydrochloride 602 Nystatin 598 Oxiconazole nitrate 601 Sulconazole nitrate 601 Terbinifine hydrochloride 602 Terconazole 601 Tioconazole 601 Tolnaftate 602...

Antifungal application of non - antifungal drugs 1

Echinocandin antifungal drugs.

The echinocandins are large lipopeptide molecules that are inhibitors of beta-(1,3)-glucan synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins are rapidly fungicidal against most Candida spp and fungistatic against Aspergillus spp. They are not active at clinically relevant concentrations against Zygomycetes, Cryptococcus neoformans, or Fusarium spp. No ...